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Bone Marrow Transplant

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Bone marrow transplantation, also known as hematopoietic stem cell transplantation is a surgical procedure where healthy cells from the marrow, are infused into another patient’s diseased or damaged bone marrow. Bone marrow transplantation can also be used to treat patients suffering from certain types of cancer.

There are two main types of hematopoietic stem cell transplantation:

● Autologous hematopoietic stem cell transplant – The bone marrow is harvested from the patient’s own body and injected where it is needed
● Allogeneic hematopoietic stem cell transplant – The cells are harvested from a donor

Bone marrow transplantation is mainly used to help patients that:

● Need high doses of radiation or chemotherapy
● Need to replace damaged or diseased marrow
● Need new healthy stem cells which can kill cancer cells directly, without other treatments

Bone Marrow Transplant Candidates

A bone marrow transplant procedure is recommended for patients suffering from:

● Adrenoleukodystrophy
● Acute leukemia
● Aplastic anemia
● Chronic leukemia
● Hodgkin's lymphoma
● Inborn errors of metabolism
● Plasma cell disorders
● Immune deficiencies
● And others

Am I Suitable for Bone Marrow Transplant?

Bone marrow transplantation is not recommended for patients in the final stages of cancer. The patient needs to be in a good state of health for this procedure. The bone marrow transplant procedure is usually performed when the disease is in remission.

Preparing for Bone Marrow Transplant

The patient will need to be submitted to hospital a few days before the bone marrow transplant is set to begin. A special tube is inserted into one of the patient’s larger veins in the chest area. This tube is essential for the bone marrow transplant procedure, which will be performed later.

Blood samples are collected through the tube and the patient will be administered certain necessary drugs. Large doses of Chemotherapy are then administered to the patient. Sometimes radiation is also used. Chemotherapy is used to destroy diseased or damaged stem cells in the marrow. The chemotherapy also ensures that the patient won’t reject the new stem cells when they are infused into the body. Once these steps are performed, the actual bone marrow transplant procedure can begin.

How is Bone Marrow Transplant Performed?

The hematopoietic stem cell transplantation procedure can be divided into two separate stages:

● Harvesting
General anaesthesia is administered to the patient or donor. The doctor will then introduce a needle deep into the hip bone and extract the marrow into a syringe. The sternum can also be used to harvest marrow. The doctor will proceed to repeat the process until around a litre of marrow is harvested – the marrow will then be subjected to chemotherapy if it is harvested from the patient and not a separate donor. This will ensure that the marrow is fully healthy.

The procedure usually lasts about an hour. The marrow will then regenerate in a few weeks.

● Transplant
The transplant stage of the bone marrow transplant procedure is very similar to a blood transfusion. The patient’s pre-inserted tube is used to inject the bone marrow cells directly into the bloodstream. Once these cells are injected, they will slowly find their way to the patient’s own bone marrow and begin producing platelets, white blood cells and red blood cells.

The transplant usually lasts about an hour. Some patients may feel nausea or headaches during this stage of the bone marrow transplant.

Bone Marrow Transplant Summary

Anesthesia

General anesthetic

Duration of Operation

1 hour

Bone Marrow Transplant Recovery

The bone marrow transplant recovery period is different for donors and recipients. The average donor can return to normal activities and work in 1 to 7 days. The marrow will regenerate in a few weeks.

The recovery time for the recipient is much longer, between 6 and 12 months. Most complications occur in the first 100 days after the bone marrow transplant procedure.

Bone Marrow Transplant Risks and Complications

Bone marrow transplant complications can include:

● Graft failure
● Graft vs host disease
● Cataracts
● Serious infection following chemotherapy

Bone Marrow Transplant Side Effects

Bone marrow transplant side effects can include:

● Pain
● Nausea
● Diarrhea
● Intestinal cramps
● Hair loss
● Skin rashes

Bone Marrow Transplant Success Rates

The average bone marrow transplant success rate is 69% for patients with an unrelated donor and 79% for patients with a related donor.

Before and After Bone Marrow Transplant

Around 85% of patients that underwent hematopoietic stem cell transplantation improve their life expectancy by 10 or more years.

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Acibadem Maslak Hospital

Istanbul, Turkey
7 reviews
JCI - Joint Commission International ISO 9001:2008 - International Organization for Standardization
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Florence Nightingale Istanbul

Istanbul, Turkey
6 reviews
JCI - Joint Commission International ISO 9001:2000 - International Organization for Standardization TÜV SÜD - Technical Control Unit
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Medipol Mega University Hospital

Istanbul, Turkey
7 reviews
JCI - Joint Commission International
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Medicana International Istanbul

Istanbul, Turkey
1 review
JCI - Joint Commission International
FROM€ 41,118
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Kent Hospital

İzmir, Turkey
JCI - Joint Commission International
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Kolan International Hospital

Istanbul, Turkey
3 reviews
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Raffles Hospital Singapore

SINGAPORE, Singapore
JCI - Joint Commission International ISO 9001:2008 - International Organization for Standardization
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Indraprastha Apollo Hospital

New Delhi, India
JCI - Joint Commission International
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Average Ratings:  
24 reviews

Bone Marrow Transplant Cost

Average Bone Marrow Transplant costs are € 41,118, based on Bone Marrow Transplant prices from 8 clinics.

Bone Marrow Transplant prices vary greatly depending on the clinic and the location. For example, Bone Marrow Transplant in Turkey is a popular option where Bone Marrow Transplant costs as low as € 41,118.

Please note that the Bone Marrow Transplant prices listed on FlyMedi are the average price for Bone Marrow Transplant procedures. Clinics may ask you to provide them with specific information about your medical condition in order to provide you a detailed cost estimate for Bone Marrow Transplant procedures. To receive a personalized Bone Marrow Transplant quote, please click HERE.

Bone Marrow Transplant FAQ

?
What is graft vs host disease?

This is a medical condition where the donor marrow cells attack the recipient’s body.

?
Does a marrow donor face any risks?

Generally no, the only risk is the general anaesthesia used to harvest marrow.

?
What are the chances of having a donor in my family?

Around 30% - 70% of patients do not have a donor in their family.