Kidney transplantation is a must for many patients suffering from chronic renal diseases. After all, being dependent on hemodialysis or peritoneal dialysis is time-consuming, not to mention that patients using it live shorter than others who got a kidney transplant.
Cross-kidney transplant, also known as a kidney paired transplant or kidney paired donation, is a promising alternative for patients who need kidney transplantation but their donors turn up to be not suitable (positive) as a result of cross-matching from blood and tissue testing. In a cross-kidney transplant, patients who cannot accept their own partner’s kidney for immunological reasons are given a kidney from the partner of another patient in exchange for a kidney from their own partner. There is no difference in the medical indications between direct and indirect living donation.
Kidney transplantation is a life-saving treatment of choice for patients with end-stage renal disease (ESRD). There are several factors such as the degree of HLA compatibility between donor and the recipient, pretransplant blood transfusions, the recipient’s state of immunoreactivity and sensitization, immunosuppressive therapy is given in post-operative period, etc. is determining together the success of transplant result. Donor selection is accepted as the most critical factor for the long-term success of the transplantation. Crossmatch between…
According to the declaration of renal experts from European Renal Association — European Dialysis and Transplant Association and American Society of Nephrology, chronic kidney diseases affects more than 850 million people worldwide as of 2018. This is twice the number of diabetics (422 million) and more than 20 times the number of people with cancer (42 million). 10 percent of men and nearly 12 percent of women around the world have kidney disease, and as much as 10.5 million people need dialysis or a kidney transplant.