The cornea is the clear, front window of the eye. It helps focus light into the eye so that you can see. The cornea is made of layers of cells. These layers work together to protect your eye and provide clear vision. Your cornea must be clear, smooth and healthy for good vision. If it is swollen or damaged, your eyes cannot focus the light properly. As a result, your vision is blurry, or you see glare. If your cornea cannot heal or repair itself, your ophthalmologist may recommend a corneal transplant.
Loss of optical clarity occurs when the cornea is damaged by injury or disease. When irreversible, blindness occurs. To date, the widely accepted treatment is transplantation with human donor corneas. However, in many countries, the demand for good quality tissue exceeds the supply. In addition, some conditions are not amenable for donor transplantation. Hence, artificial corneal substitutes are using to address the shortage of human donor tissues as well as the current disadvantages in some clinical indications, which include immune rejection.
There are several reasons why you may need a new cornea:
• Complications from LASIK or PRK surgery
• Degenerative eye conditions called corneal dystrophies which affect the clarity of the cornea.
• Scarring from previous infections, such as bacterial, fungal, and viral (e.g., Herpes simplex) infections.
• Keratoconus, a condition associated with thinning of the cornea and an irregular shape.
Artificial Corneal Transplant (37 Clinics)