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Bone Marrow Transplant (4 Clinics)

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Acibadem Maslak Hospital
Istanbul, Turkey
Acibadem Maslak Hospital Verified
  • Pick up service from airport
  • ISO 9001:2008 and JCI accreditations
  • Has LEED GOLD Certificate
  • 231 patient rooms
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Medipol Mega University Hospital
Istanbul, Turkey
Medipol Mega University Hospital Verified
  • Turkey's one of the largest hospitals
  • Turkey's first private medical complex
  • Accredited by ISO, JCI and the TUV
  • Online doctor consultations
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Florence Nightingale Istanbul
Istanbul, Turkey
Florence Nightingale Istanbul Verified
  • Accredited by ISO, JCI and the TUV
  • Free airport pickup and free VIP transfers
  • Translation services in English, German and more
  • 700 bed capacity
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Kolan International Hospital
Istanbul, Turkey
Kolan International Hospital Verified
  • Over 450 medical staff
  • Accredidated JCI
  • 174 beds
  • Assistance with flight and hotel bookings
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OUR PATIENTS

What Our Patients Say

EXCELLENT star star

Based on 222 reviews on Trustpilot
Ashab Khamchiev, Turkey
star star Aug 2020

Excellent work

Excellent work. Thank you very much. Yasmine and Mustafa Helped through the whole process of surgery and recovery.

Betty, Turkey
star star Aug 2020

Stumbled across Flymedi while I was…

Stumbled across Flymedi while I was looking for a place to get my nose done. I was contacted immediately by Mustafa and he offered me every detail that I needed. Overall the experience with them was great and I m extremely pleased with how smoothly everything went.

bellaxws, Turkey
star star Aug 2020

(Chin and neck liposuction) great experience with Abud

I found flymedi while I was looking for a doctor in Istanbul to do a chin and neck liposuction. Abud from Flymedi contacted me and he was great from the beginning until even after I went back home, he took care of everything and was always available, definitely the right person for this experience! My doctor (Dr Ozge Ergun) was also great, I'm very satisfied and I can only recommend Flymedi, the best place to find your treatment!

Ellis McLintock, Turkey
star star Aug 2020

5* service

From start to finish my experience with Flymedi was exceptional. The coordinator, Abud worked hard at finding the right surgeon for me. He was constantly in contact while I was away to ensure everything went smoothly. I honestly could not be happier with the company. Dr Ozge has done an exceptional job too. Thank you Abud for making me feel confident again!

Joseph, Poland
star star Jun 2020

Great Service

After a long research for hair transplant, I came across Flymedi. I had several reasons to get this service from them such as getting rid of the bureaucratic process, handling accommodation issues, personal assistant, etc. I felt comfortable once it is done by Flymedi as full of customer-oriented style, I was just worried about the surgery which went well too! Thank you Flymedi team. Make sure that I will be letting people know your passion for helping patients who admit to have surgery done in Poland.

Recommended For Bone Marrow Transplant

For the patients who are suffering from the listed conditions, bone marrow transplant practice is recommended:

● Adrenoleukodystrophy
● Acute leukemia
● Aplastic anemia
● Chronic leukemia
● Hodgkin's lymphoma
● Inborn errors of metabolism
● Plasma cell disorders
● Immune deficiencies

Not Recommended For Bone Marrow Transplant

For the patients who are suffering from advanced stages of cancer, bone marrow transplantation is not suggested. For bone marrow transplant operation, the patient must be in an overall good state of health. This operation is generally performed when the disease is in remission.

Duration Of Operation

1 hour

Overview

Bone marrow transplantation, also called hematopoietic stem cell transplantation is a surgical practice in which healthy cells from the marrow, are infused into another patient’s diseased or damaged bone marrow. For the patients who are suffering from some other kinds of cancer, bone marrow transplantation can be used to treat them as well.


Hematopoietic stem cell transplantation has two major types, which are:

● Autologous hematopoietic stem cell transplant – The bone marrow is harvested from the patient’s body itself and injected where the treatment is required
● Allogeneic hematopoietic stem cell transplant – In this method, from a donor, the cells are harvested

Bone marrow transplantation is usually performed for the patients who:

● Need high doses of radiation or chemotherapy
● Need to replace damaged or diseased marrow
● Need new healthy stem cells which can kill cancer cells directly, without other treatments

Preparation

A couple of days before the bone marrow transplant operation, the patient needs to stay in the hospital. To the patient’s larger veins in the chest area, a special tube is inserted. This tube is very important for the bone marrow transplant operation, which will be performed later.

With the use of the tube, blood samples would be gathered, and some drugs would be given to the patient. After, large doses of chemotherapy are administered to the patient. Occasionally radiation is used as well. To eliminate diseased or damaged stem cells in the marrow, chemotherapy is used. Also, with chemotherapy, it is ensured that the patient’s body would not reject the new stem cells when they are infused into the patient. Once these steps are completed, the real bone marrow transplant operation starts.

How It Is Performed

There are two stages of hematopoietic stem cell transplantation operation that are:

● Harvesting
During this procedure, to the patient or donor, general anesthesia is administered. After that, the doctor would induce a needle deep into the hip bone and extract the marrow into a syringe. The sternum can also be used to harvest marrow. The doctor will proceed to repeat the process until around a liter of marrow is harvested – the marrow will then be subjected to chemotherapy if it is harvested from the patient and not a separate donor. This way, it can be ensured that the marrow is completely healthy.

The process generally takes about an hour. After, the marrow would regenerate in a couple of weeks.

● Transplant
The transplant stage is very similar to a blood transfusion procedure. The pre-inserted tube that is in the patient’s body is used to inject the bone marrow cells straight into the bloodstream. Once these cells are injected, they will slowly find their way to the patient's own bone marrow and begin producing platelets, white blood cells, and red blood cells.

The transplant process generally takes an hour. During this process, some patients might feel nausea or headaches.

Recovery

The recovery period of bone marrow transplant is different for the donors and the recipients. On average, the donors would return to their daily activities and work in 1-7 days. The marrow would regenerate in a couple of weeks.

For the recipient, the recovery period is much longer, which is around 6-12 months. Most of the complications happen in the first 100 days after the bone marrow transplant operation.

Risks

Bone marrow transplant procedure has some complications that involve:

● Graft failure● Graft vs. host disease
● Cataracts
● Serious infection after chemotherapy

Side Effects

There are several side effects of bone marrow transplant, such as:

● Pain
● Nausea
● Diarrhea
● Intestinal cramps
● Hair loss
● Skin rashes

Success Rates

The average success rate of bone marrow transplant is 69% for the patients with an unrelated donor and 79% for the patients with a related donor.

Before And After

Around 85% of the patients who had hematopoietic stem cell transplantation, their life expectancy is improved by 10 or more years.

Faq

– What is graft vs. host disease?
In this condition, the donor marrow cells assault the recipient’s body.

– Does a marrow donor face any risks?
Usually no, the risks are only related to the use of general anesthesia.

– What are the chances of having a donor in my family?
The rate of patients who do not have a donor in their family is around 30% - 70%.

Extra Content

This content is written and reviewed by our medical content team in October, 2019.